The severity of nonalcoholic fatty liver disease is associated with gut dysbiosis and shift in the metabolic function of the gut microbiota

Boursier, Jérôme; Mueller, Olaf; Barret, Matthieu; Verdelho Machado, Mariana; Fizanne, Lionel; Araújo-Pérez, Félix; D. Guy, Cynthia; C. Seed, Patrick; F. Rawls, John; A. David, Lawrence; Hunault, Gilles; Oberti, Frédéric; Calès, Paul; Mae Diehl, Anna

doi:10.1002/hep.28356

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The severity of nonalcoholic fatty liver disease is associated with gut dysbiosis and shift in the metabolic function of the gut microbiota

Published in Hepatology • Nov 24, 2015

Authors:

Jérôme Boursier

Olaf Mueller

Matthieu Barret

Abstract

UNLABELLED: Several animal studies have emphasized the role of gut microbiota in nonalcoholic fatty liver disease (NAFLD). However, data about gut dysbiosis in human NAFLD remain scarce in the literature, especially studies including the whole spectrum of NAFLD lesions. We aimed to evaluate the asso...

Subject

Dysbiosis

Nonalcoholic fatty liver disease

Gut flora

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