Metagenomic analysis of faecal microbiome as a tool towards targeted non-invasive biomarkers for colorectal cancer

Yu, Jun; Feng, Qiang; H. Wong, Sunny; Zhang, Dongya; yi Liang, Qiao; Qin, Youwen; Tang, Longqing; Zhao, Hui; Stenvang, Jan; Li, Yanli; Wang, Xiaokai; Xu, Xiaoqiang; Chen, Ning; Ka Kei Wu, William; Y. Al‐Aama, Jumana; Jørgen Nielsen, Hans; Kiilerich, Pia; A. H. Jensen, Benjamin; On Yau, Tung; Lan, Zhou; Jia, Huijue; Li, Junhua; Xiao, Liang; Y. Lam, Thomas; C. Ng, Siew; S.L. Cheng, Alfred; Wai‐Sun Wong, Vincent; K.L. Chan, Francis; Xu, Xun; Yang, Huanming; Madsen, Lise; Datz, Christian; Tilg, Herbert; Wang, Jian; Wang, Jian; Brünner, Nils; Kristiansen, Karsten; Arumugam, Manimozhiyan; J.�Y. Sung, Joseph; Wang, Jun; Wang, Jun

doi:10.1136/gutjnl-2015-309800

Public

Metagenomic analysis of faecal microbiome as a tool towards targeted non-invasive biomarkers for colorectal cancer

Published in Gut • Sep 25, 2015

Authors:

Jun Yu

Qiang Feng

Sunny H. Wong

Abstract

OBJECTIVE: To evaluate the potential for diagnosing colorectal cancer (CRC) from faecal metagenomes. DESIGN: We performed metagenome-wide association studies on faecal samples from 74 patients with CRC and 54 controls from China, and validated the results in 16 patients and 24 controls from Denmark....

Subject

Metagenomics

Microbiome

Colorectal cancer

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