Clinicopathologic analysis of <scp>TAFRO</scp> syndrome demonstrates a distinct subtype of <scp>HHV</scp>‐8‐negative multicentric Castleman disease

Iwaki, Noriko; C. Fajgenbaum, David; S. Nabel, Christopher; Gion, Yuka; Kondo, Eisei; Kawano, Mitsuhiro; Masunari, Taro; Yoshida, Isao; Moro, Hiroshi; Nikkuni, Koji; Takai, Kazue; Matsue, Kosei; Kurosawa, Mitsutoshi; Hagihara, Masao; Saito, Akio; Okamoto, Masataka; Yokota, Kenji; Hiraiwa, Shinichiro; Nakamura, Naoya; Nakao, Shinji; Yoshino, Tadashi; Sato, Yasuharu

doi:10.1002/ajh.24242

Public

Clinicopathologic analysis of TAFRO syndrome demonstrates a distinct subtype of HHV‐8‐negative multicentric Castleman disease

Published in American Journal of Hematology • Nov 17, 2015

Authors:

Noriko Iwaki

David C. Fajgenbaum

Christopher S. Nabel

Abstract

Multicentric Castleman disease (MCD) describes a heterogeneous group of disorders involving systemic inflammation, characteristic lymph node histopathology, and multi-organ dysfunction because of pathologic hypercytokinemia. Whereas Human Herpes Virus-8 (HHV-8) drives the hypercytokinemia in a cohor...

Subject

Anasarca

Organomegaly

Medicine

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