Impact of EGFR inhibitor in non-small cell lung cancer on progression-free and overall survival: a meta-analysis.

Khoon Lee, Chee; Brown, Chris; J Gralla, Richard; Hirsh, Vera; Thongprasert, Sumitra; Tsai, Chun-Ming; Huat Tan, Eng; Chung-Man Ho, James; Tong Chu, Da; Zaatar, Adel; Anne Osorio Sanchez, Jemela; Van Vu, Vu; Siu Kie Au, Joseph; Inoue, Akira; Ming Lee, Siow; Gebski, Val; Chih-Hsin Yang, James

doi:10.1093/jnci/djt072

Public

Impact of EGFR inhibitor in non-small cell lung cancer on progression-free and overall survival: a meta-analysis.

Published in Journal of the National Cancer Institute • May 1, 2013

NobleIDark:/48914/w1/20260526/E2071C47Record on NobleID

Authors:

Chee Khoon Lee

,

Chris Brown

,

Richard J Gralla

Abstract

BACKGROUND: The epidermal growth factor receptor (EGFR) signaling pathway is crucial for regulating tumorigenesis and cell survival and may be important in the development and progression of non-small cell lung cancer (NSCLC). We examined the impact of EGFR-tyrosine kinase inhibitors (TKIs) on progr...

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