A recombinant, chimeric tetravalent dengue vaccine candidate based on a dengue virus serotype 2 backbone

E. Osorio, Jorge; Wallace, Derek; T. Stinchcomb, Dan

doi:10.1586/14760584.2016.1128328

Public

A recombinant, chimeric tetravalent dengue vaccine candidate based on a dengue virus serotype 2 backbone

Published in Expert Review of Vaccines • Dec 4, 2015

Authors:

Jorge E. Osorio

Derek Wallace

Dan T. Stinchcomb

Abstract

Dengue fever is caused by infection with one of four dengue virus (DENV) serotypes (DENV-1-4), necessitating tetravalent dengue vaccines that can induce protection against all four DENV. Takeda's live attenuated tetravalent dengue vaccine candidate (TDV) comprises an attenuated DENV-2 strain plus ch...

Subject

Dengue fever

Dengue vaccine

Dengue virus

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