Haplotypes of the endothelial protein C receptor (EPCR) gene are not associated with severe malaria in Tanzania

Hansson, Helle; Turner, Louise; Møller, Line; W. Wang, Christian; T. R. Minja, Daniel; Gesase, Samwel; P. Mmbando, Bruno; Christian Bygbjerg, Ib; G. Theander, Thor; Lusingu, John; Alifrangis, Michael; Lavstsen, Thomas

doi:10.1186/s12936-015-1007-6

Public

Haplotypes of the endothelial protein C receptor (EPCR) gene are not associated with severe malaria in Tanzania

Published in Malaria Journal • Dec 1, 2015

Authors:

Helle Hansson

Louise Turner

Line Møller

Abstract

BACKGROUND: Endothelial protein C receptor (EPCR) was recently identified as a key receptor for Plasmodium falciparum erythrocyte membrane protein 1 mediating sequestration of P. falciparum-infected erythrocytes in patients suffering from severe malaria. Soluble EPCR (sEPCR) inhibits binding of P. f...

Subject

Endothelial protein C receptor

Tanzania

Parasitology

Research Assistant

AI chat, annotations, notes & similar papers

Finding related papers...

Discussions

(0)

No comments yet

Be the first to share your thoughts!