The Current Scientific and Legal Status of Alternative Methods to the LD50 Test for Botulinum Neurotoxin Potency Testing

Adler, Sarah; Bicker, Gerd; Bigalke, Hans; Bishop, Christopher; Blümel, Jörg; Dressler, Dirk; Fitzgerald, Joan; Gessler, Frank; Heuschen, Heide; Kegel, Birgit; Luch, Andreas; Milne, Catherine; M. Pickett, Andrew; Ratsch, Heidemarie; Ruhdel, Irmela; Sesardic, Dorothea; L. Stephens, Martin; Stiens, Gerhard; D. Thornton, Peter; Thürmer, René; Vey, Martin; Spielmann, Horst; Grune, Barbara; Liebsch, Manfred

doi:10.1177/026119291003800401

Public

The Current Scientific and Legal Status of Alternative Methods to the LD50 Test for Botulinum Neurotoxin Potency Testing

Published in Alternatives to Laboratory Animals • Aug 1, 2010

Authors:

Sarah Adler

Gerd Bicker

Hans Bigalke

Abstract

An Expert Meeting on The Current Scientific and Legal Status of Alternative Methods to the LD50 Test for Botulinum Neurotoxin (BoNT) Potency Testing was organised by the Centre for Documentation and Evaluation of Alternatives to Animal Experiments (ZEBET) at the Federal Institute for Risk Assessment...

Subject

Animal welfare

Documentation

Harmonization

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