Resveratrol Treatment after Status Epilepticus Restrains Neurodegeneration and Abnormal Neurogenesis with Suppression of Oxidative Stress and Inflammation.

Vikas, Mishra,; Bing, Shuai,; Maheedhar, Kodali,; Geetha A, Shetty,; Bharathi, Hattiangady,; Xiaolan, Rao,; Ashok K, Shetty,

doi:10.1038/srep17807

Public

Resveratrol Treatment after Status Epilepticus Restrains Neurodegeneration and Abnormal Neurogenesis with Suppression of Oxidative Stress and Inflammation.

Published in Scientific reports • Dec 7, 2015

Authors:

Mishra, Vikas

Shuai, Bing

Kodali, Maheedhar

Abstract

Antiepileptic drug therapy, though beneficial for restraining seizures, cannot thwart status epilepticus (SE) induced neurodegeneration or down-stream detrimental changes. We investigated the efficacy of resveratrol (RESV) for preventing SE-induced neurodegeneration, abnormal neurogenesis, oxidative...

Subject

Animals

Behavior

Animal

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