Relationship Between Pneumocystis carinii Burden and the Degree of Host Immunosuppression in an Airborne Transmission Experimental Model

Khalife, Sara; Chabé, Magali; Gantois, Nausicaa; Audebert, Christophe; Pottier, Muriel; Hlais, Sani; Pinçon, Claire; Chassat, Thierry; Pierrot, Christine; Khalife, Jamal; Aliouat‐Denis, Cécile‐Marie; Moukhtar Aliouat, El

doi:10.1111/jeu.12280

Public

Relationship Between Pneumocystis carinii Burden and the Degree of Host Immunosuppression in an Airborne Transmission Experimental Model

Published in Journal of Eukaryotic Microbiology • Oct 28, 2015

Authors:

Sara Khalife

Magali Chabé

Nausicaa Gantois

Abstract

To quantitatively assess the risk of contamination by Pneumocystis depending on the degree of immunosuppression (ID) of the exposed rat hosts, we developed an animal model, where rats went through different doses of dexamethasone. Then, natural and aerial transmission of Pneumocystis carinii occurre...

Subject

Pneumocystis carinii

Pneumocystosis

Immunosuppression

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