Role of ErbB Receptors in Cancer Cell Migration and Invasion

Appert-Collin, Aline; Hubert, P.; Crémel, Gérard; Bennasroune, Amar

doi:10.3389/fphar.2015.00283

Public

Role of ErbB Receptors in Cancer Cell Migration and Invasion

Published in Frontiers in Pharmacology • Nov 24, 2015

Authors:

Aline Appert-Collin

P. Hubert

Gérard Crémel

Abstract

Growth factors mediate their diverse biologic responses (regulation of cellular proliferation, differentiation, migration and survival) by binding to and activating cell-surface receptors with intrinsic protein kinase activity named receptor tyrosine kinases (RTKs). About 60 RTKs have been identifie...

Subject

Receptor tyrosine kinase

ErbB

ERBB4

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