Dengue viruses cluster antigenically but not as discrete serotypes

C. Katzelnick, Leah; M. Fonville, Judith; D. Gromowski, Gregory; Bustos‐Arriaga, José; Green, Angela; L. James, Sarah; Lau, Louis; Montoya, Magelda; Wang, Chunling; A. VanBlargan, Laura; A. Russell, Colin; Myat Thu, Hlaing; C. Pierson, Theodore; Buchy, Philippe; Aaskov, John; L. Muñoz‐Jordán, Jorge; Vasilakis, Nikos; V. Gibbons, Robert; B. Tesh, Robert; D. M. E. Osterhaus, Albert; A. M. Fouchier, Ron; P. Durbin, Anna; P. Simmons, Cameron; C. Holmes, Edward; Harris, Eva; S. Whitehead, Stephen; J. Smith, Derek

doi:10.1126/science.aac5017

Public

Dengue viruses cluster antigenically but not as discrete serotypes

Published in Science • Sep 18, 2015

Authors:

Leah C. Katzelnick

Judith M. Fonville

Gregory D. Gromowski

Abstract

The four genetically divergent dengue virus (DENV) types are traditionally classified as serotypes. Antigenic and genetic differences among the DENV types influence disease outcome, vaccine-induced protection, epidemic magnitude, and viral evolution. We characterized antigenic diversity in the DENV ...

Subject

Dengue fever

Virology

Serotype

Research Assistant

AI chat, annotations, notes & similar papers

Finding related papers...

Discussions

(0)

No comments yet

Be the first to share your thoughts!