No Perinatal HIV-1 Transmission From Women With Effective Antiretroviral Therapy Starting Before Conception

Mandelbrot, Laurent; Tubiana, Roland; Le Chenadec, Jérôme; Dollfus, Catherine; Faye, Albert; Pannier, E.; Matheron, Sophie; Khuong, Marie-Aude; Garrait, Valérie; Reliquet, Véronique; Devidas, Alain; Berrébi, Alain; Allisy, C; Elleau, Christophe; Arvieux, C.; Rouzioux, Christine; Warszawski, Josiane; Blanche, Stéphane; the ANRS-EPF Study Group, for; Mandelbrot, Laurent; Crenn‐Hébert, Catherine; Floch-Tudal, Corinne; Mazy, Fabienne; Joras, Marine; Meier, Françoise; Mortier, Emmanuel; Ceccaldi, Pierre‐François; Banigé, Maïa; Uludag, Agnès; Zarouk, Virginie; Lefort, A.; Hittinger, Gilles; Chamouilli, Jean-Marc; Burle, Christian; Lafeuillade, Alain; Medus, Marie; Bachelard, Germaine; Dendale-Nguyen, Joëlle; Guimard, Thomas; Guimard, Karine; Brossier, Jean-Pierre; Van de Perre, Philippe; Esnault, Jean-Luc; Bollengier Stragier, Olivier; Leautez‐Nainville, Sophie; Martha, Sandrine-Anne; Martha, Benoît; Maurel, E.; Françoise, Michel; Barat, Muriel; Murger, Patricia; Rouha, Mahfoud; Lumbroso, P; Checoury, A; Perfezou, Pascale; Blondin, Gilles; Ansart, Séverine; de Saint Martin, Luc; Le Moine, Philippe; Daniel, Corinne; Calvez, Christian; Boutard, Emmanuelle; Arvieux, C.; Bauville, Estelle; Dupre, Christelle; Poinsignon, Yves; Grelier, Anne; Mousset, Gaétane; Cudeville, Corinne; Niault, Mathilde; Belzic, Isabelle; Moreau, Philippe; Le Coz, Marie-Françoise; Luycx Vaillant, Odile; Vitrat, Virginie; Tardif, D.; Gaillat, Jacques; Vanderbergh, Anne; Braig, Suzanne; Dehlinger-Paul, Marion; Mohamed, Khaled; Heller-Roussin, Brigitte; Winter, Cécile; Firtion, Ghislaine; Pannier, E.; Costa, Myriam; Launay, Odile; Salmon Ceron, Dominique; Matheron, Sophie; Rajguru, Mandovi; Elaoun, Neila; Allal, Lahcene; Azria, Élie; Bourgeois Moine, Agnès; Garrait, Valérie; Hau, Isabelle; Touboul, Claudine; Ratsimbazafy, Lanto; Kommé, Christiane; Elharrar, Brigitte; Labaune, Jean-Marc; Cotte, Laurent; Rudigoz, R.-C.; Elleau, Christophe; Runel-Belliard, Camille; Pistone, Thierry; Muanza, Blandine; Broustal, E.; Duval-Arnould, Marc; Carpentier, Bénédicte; Dienga, Etienne; Partisani, Marialuisa; Entz‐Werlé, Natacha; David, Éric; Rey, David; Seaume, Hervé; Ducrocq, Sarah; Bailly-Salin, Philippe; Tricoire, J; Berrebi, Alain; Cayla, Claudine; Chacé, Anne; Metheron, Isabelle; Boutemy, Anne; Armangaud, Didier; Couderc, Sophie; Routier, Corinne; Alissa, Alain; Questiaux, E.; S. Zakaria, Ahmed; Dauphin, Hélène; Goissen, Céline; Belloy, Marie; Delassus, Jean-Luc; Partisani, Marialuisa; Cheneau, Christine; Lang, Jean-Marie; Brault, Dominique; Allisy, C; Lebrette, Marie-Gisèle; Selleret, Lise; Hervé, François; Bolot, Pascal; Khuong-Josses, Marie-Aude; Ekoukou, Dieudoné; Bounan, Stéphane; Blanche, Stéphane; Lemercier, Delphine; Frange, Pierre; Veber, Florence; Fisher, Alain; Granier, Michèle; Devidas, Alain; Nguyen, Rose; May, Adrien; Chabrol, Amélie; Chevojon, Pierre; Abdallah Moussa, Zaitoun; Pluchart, Claire; Rouger, Christine; Tubiana, Roland; Bonmarchand, Manuela; Shneider, Luminata; Caby, Fabienne; Calin, Ruxandra-Oana; Coursol, Anne; Chambrin, V.; Labrune, Philippe; Clech, Laure; Pauly-Ravelly, Isolde; Moalim, Raghad; Sanchez, Lydie; Johnson, Ama; Lachassine, Eric; Benoist, L.; Jeantils, Vincent; Gaudelus, J.; Benbara, Amélie; Borgne, Anne; Karaoui, Leïla; Lefevre Elbert, Véronique; Bongain, A.; Monpoux, Fabrice; Deville, Anne; Galiba, Eliane; Doumet, Antoine; Schmidt, Jean-Luc; Cravello, L.; Hubert, Claire; Dollfus, Catherine; Hervé, François; Tabone, Marie‐Dominique; Courcoux, Mary‐France; Leverger, Guy; Carbonne, B.; Pinquier, Didier; Clavier, Brigitte; Pinto-Cardoso, Gaëlle; Faye, Albert; Matheron, Sophie; Lévine, Martine; Bellaton Marouts, Erianna; Borie, Constance; Boissinot, Christine; Peretti, Delphine; Fourcade, Corinne; Chirouze, Catherine; Hafner Mauvais, Cécile; Reliquet, Véronique; Brunet-Cartier, Cécile; Winer, Norbert; Vaucel, Edouard; Briandet, Claire; Brouard, Jacques; Chalvon Demersay, A.; Hentgen, Véronique; Messaoudi, Fabienne; Bernard, Louis; Maakroun, Zoha; Nau, Pascale; Kébaïli, Kamila; Billiemaz, Kareen; Abrudan, Ramona; Fialaire, Pascale; Sentilhes, Loïc; Proust, Stéphanie; Arsac, Philippe; Mesnard, Louis; Werner, Evelyne; Ciraru‐Vigneron, N; Mouchnino, G; Ayral, D; Vintejoux, Emmanuelle; Lalande, Muriel; Reynes, Jacques; Segondy, Michel; De Gennes, Christiane; Clavel, C; Mazingue, Françoise; Hammou, Yamina; Ajana, Faïza; Hatchuel, Yves; Nahri, Imad; Genet, Claire; Ducroix-Roubert, Sophie; Aubrard, Yves; Constanty, Anne; Weinbreck, P.; Piet, Emilie; Jacquier, Françoise; Michau, Christophe; Safwan, Hassan; Boutet, A.; Abdelhadi, Mohamed; Elenga, Narcisse; Blanche, Stéphane; Delmas, Sandrine; Dollfus, Catherine; Faye, Albert; Frange, Pierre; Le Chenadec, Jérôme; Mandelbrot, Laurent; Perilhou, Anaïs; Rouzioux, Christine; Sibiude, Jeanne; Tubiana, Roland; Warszawski, Josiane

doi:10.1093/cid/civ578

Public

No Perinatal HIV-1 Transmission From Women With Effective Antiretroviral Therapy Starting Before Conception

Published in Clinical Infectious Diseases • Jul 21, 2015

Authors:

Laurent Mandelbrot

Roland Tubiana

Jérôme Le Chenadec

Abstract

BACKGROUND: The efficacy of preventing perinatal transmission (PT) of human immunodeficiency virus type 1 (HIV-1) depends on both viral load (VL) and treatment duration. The objective of this study was to determine whether initiating highly active antiretroviral therapy (ART) before conception has t...

Subject

Medicine

Antiretroviral therapy

Human immunodeficiency virus (HIV)

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