No Perinatal HIV-1 Transmission From Women With Effective Antiretroviral Therapy Starting Before Conception

Mandelbrot, Laurent; Tubiana, Roland; Le Chenadec, Jerome; Dollfus, Catherine; Faye, Albert; Pannier, Emmanuelle; Matheron, Sophie; Khuong, Marie-Aude; Garrait, Valerie; Reliquet, Veronique; Devidas, Alain; Berrebi, Alain; Allisy, Christine; Elleau, Christophe; Arvieux, Cedric; Rouzioux, Christine; Warszawski, Josiane; Blanche, Stéphane; the ANRS-EPF Study Group, for; Mandelbrot, Laurent; Crenn-Hebert, Catherine; Floch-Tudal, Corinne; Mazy, Fabienne; Joras, Marine; Meier, Françoise; Mortier, Emmanuel; Ceccaldi, Pierre-François; Banige, Maïa; Villemant Uludag, Agnès; Zarouk, Virginie; Lefort, Agnès; Hittinger, Gilles; Chamouilli, Jean-Marc; Burle, Christian; Lafeuillade, Alain; Medus, Marie; Bachelard, Germaine; Dendale-Nguyen, Joëlle; Guimard, Thomas; Guimard, Karine; Brossier, Jean-Pierre; Perré, Philippe; Esnault, Jean-Luc; Bollengier Stragier, Olivier; Leautez-Nainville, Sophie; Martha, Sandrine-Anne; Martha, Benoît; Maurel, Elise; Françoise, Michel; Barat, Muriel; Murger, Patricia; Rouha, Mahfoud; Lumbroso, Philippe; Checoury, Alain; Perfezou, Pascale; Blondin, Gilles; Ansart, Séverine; De Saint Martin, Luc; Le Moine, Philippe; Daniel, Corinne; Calvez, Christian; Boutard, Emmanuelle; Arvieux, Cédric; Bauville, Estelle; Dupre, Christelle; Poinsignon, Yves; Grelier, Anne; Mousset, Gaetane; Cudeville, Corinne; Niault, Mathilde; Belzic, Isabelle; Moreau, Philippe; Le Coz, Marie-Françoise; Luycx Vaillant, Odile; Vitrat, Virginie; Tardif, Didier; Gaillat, Jacques; Vanderbergh, Anne; Braig, Suzanne; Dehlinger-Paul, Marion; Mohamed, Khaled; Heller-Roussin, Brigitte; Winter, Cécile; Firtion, Ghislaine; Pannier, Emmanuelle; Costa, Myriam; Launay, Odile; Salmon Ceron, Dominique; Matheron, Sophie; Rajguru, Mandovi; Elaoun, Neila; Allal, Lahcene; Azria, Elie; Bourgeois Moine, Agnès; Garrait, Valérie; Hau, Isabelle; Touboul, Claudine; Ratsimbazafy, Lanto; Kommé, Christiane; Elharrar, Brigitte; Labaune, Jean-Marc; Cotte, Laurent; Rudigoz, René-Charles; Elleau, Christophe; Runel-Belliard, Camille; Pistone, Thierry; Muanza, Blandine; Broustal, Elisabeth; Duval-Arnould, Marc; Carpentier, Bénédicte; Dienga, Etienne; Partisani, MariaLuisa; Entz-Werle, Natacha; David, Eric; Rey, David; Seaume, Hervé; Ducrocq, Sarah; Bailly-Salin, Philippe; Tricoire, Joëlle; Berrebi, Alain; Cayla, Claudine; Chacé, Anne; Metheron, Isabelle; Boutemy, Anne; Armangaud, Didier; Couderc, Sophie; Routier, Corinne; Alissa, Alain; Questiaux, Elisabeth; Zakaria, Ahmed; Dauphin, Hélène; Goissen, Céline; Belloy, Marie; Delassus, Jean-Luc; Partisani, MariaLuisa; Cheneau, Christine; Lang, Jean-Marie; Brault, Dominique; Allisy, Christine; Lebrette, Marie-Gisèle; Selleret, Lise; Hervé, François; Bolot, Pascal; Khuong-Josses, Marie-Aude; Ekoukou, Dieudoné; Bounan, Stéphane; Blanche, Stéphane; Lemercier, Delphine; Frange, Pierre; Veber, Florence; Fisher, Alain; Granier, Michèle; Devidas, Alain; Nguyen, Rose; May, Adrien; Chabrol, Amélie; Chevojon, Pierre; Abdallah Moussa, Zaitoun; Pluchart, Claire; Rouger, Christine; Tubiana, Roland; Bonmarchand, Manuela; Shneider, Luminata; Caby, Fabienne; Calin, Ruxandra-Oana; Coursol, Anne; Chambrin, Véronique; Labrune, Philippe; Clech, Laure; Pauly-Ravelly, Isolde; Moalim, Raghad; Sanchez, Lydie; Johnson, Ama; Lachassine, Eric; Benoist, Laurence; Jeantils, Vincent; Gaudelus, Joel; Benbara, Amélie; Borgne, Anne; Karaoui, Leïla; Lefevre Elbert, Véronique; Bongain, André; Monpoux, Fabrice; Deville, Anne; Galiba, Eliane; Doumet, Antoine; Schmidt, Jean-Luc; Cravello, Ludovic; Hubert, Claire; Dollfus, Catherine; Hervé, François; Tabone, Marie-Dominique; Courcoux, Mary-France; Leverger, Guy; Carbonne, Bruno; Pinquier, Didier; Clavier, Brigitte; Pinto-Cardoso, Gaelle; Faye, Albert; Matheron, Sophie

doi:10.1093/cid/civ578

Public

No Perinatal HIV-1 Transmission From Women With Effective Antiretroviral Therapy Starting Before Conception

Shared by NobleBlocks on Jul 21, 2015 • 12:00 AM UTC

Authors:

Laurent Mandelbrot

Roland Tubiana

Jerome Le Chenadec

Abstract

Abstract Background. The efficacy of preventing perinatal transmission (PT) of human immunodeficiency virus type 1 (HIV-1) depends on both viral load (VL) and treatment duration. The objective of this study was to determine whether initiating highly active antiretroviral therapy (ART) before concept...

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