TBAI/TBHP-catalyzed [3 + 2]cycloaddition/oxidation/aromatization cascade and online ESI-MS mechanistic studies: synthesis of pyrrolo[2,1-<i>a</i>]isoquinolines and indolizino[8,7-<i>b</i>]indoles

Nekkanti, Shalini; Praveen Kumar, Niggula; Sharma, Pankaj; Kamal, Ahmed; M. Nachtigall, Fabiane; Forero‐Doria, Oscar; S. Santos, Leonardo; Shankaraiah, Nagula

doi:10.1039/c5ra24629f

Public

TBAI/TBHP-catalyzed [3 + 2]cycloaddition/oxidation/aromatization cascade and online ESI-MS mechanistic studies: synthesis of pyrrolo[2,1-a]isoquinolines and indolizino[8,7-b]indoles

Shared by NobleBlocks on Dec 23, 2015 • 12:00 AM UTC

Authors:

Shalini Nekkanti

Niggula Praveen Kumar

Pankaj Sharma

Abstract

A facile [3 + 2]cycloaddition/oxidation/aromatization cascade reaction for the synthesis of pyrrolo[2,1-a]isoquinolines and indolizino[8,7-b]indoles has been developed by employing tert-butyl hydroperoxide (TBHP) and tetrabutylammonium iodide (TBAI).

Subject

Aromatization

Cycloaddition

Catalysis

Finding related papers...

Discussions

(0)

No comments yet

Be the first to share your thoughts!