Neoadjuvant 5-FU or Capecitabine Plus Radiation With or Without Oxaliplatin in Rectal Cancer Patients: A Phase III Randomized Clinical Trial

J. Allegra, Carmen; Yothers, Greg; J. O’Connell, Michael; W. Beart, Robert; F. Wozniak, Timothy; C. Pitot, Henry; F. Shields, Anthony; C. Landry, Jerome; P. Ryan, David; Arora, Amit; Evans, Lisa; Bahary, Nathan; S. Soori, Gamini; F. Eakle, Janice; M. Robertson, John; F. Moore, Dennis; Russell Mullane, Michael; T. Marchello, Benjamin; J. Ward, Patrick; Sharif, Saima; S. Roh, Mark; Wolmark, Norman

doi:10.1093/jnci/djv248

Public

Neoadjuvant 5-FU or Capecitabine Plus Radiation With or Without Oxaliplatin in Rectal Cancer Patients: A Phase III Randomized Clinical Trial

Published in JNCI Journal of the National Cancer Institute • Sep 14, 2015

Authors:

Carmen J. Allegra

Greg Yothers

Michael J. O’Connell

Abstract

BACKGROUND: National Surgical Adjuvant Breast and Bowel Project R-04 was designed to determine whether the oral fluoropyrimidine capecitabine could be substituted for continuous infusion 5-FU in the curative setting of stage II/III rectal cancer during neoadjuvant radiation therapy and whether the a...

Subject

Capecitabine

Oxaliplatin

Medicine

Research Assistant

AI chat, annotations, notes & similar papers

Finding related papers...

Discussions

(0)

No comments yet

Be the first to share your thoughts!