Extensive Modulation of the Fecal Metagenome in Children With Crohn’s Disease During Exclusive Enteral Nutrition

Quince, Christopher; Zeeshan Ijaz, Umer; Loman, Nick; Murat Eren, A.; Saulnier, Delphine; A. Russell, Julie; Haig, Sarah–Jane; Calus, Szymon; Quick, Joshua; R. Barclay, Andrew; Bertz, Martin; Blaut, Michaël; Hansen, Richard; McGrogan, Paraic; K. Russell, Richard; A. Edwards, Christine; Gerasimidis, Konstantinos

doi:10.1038/ajg.2015.357

Public

Extensive Modulation of the Fecal Metagenome in Children With Crohn’s Disease During Exclusive Enteral Nutrition

Published in The American Journal of Gastroenterology • Nov 3, 2015

Authors:

Christopher Quince

Umer Zeeshan Ijaz

Nick Loman

Abstract

OBJECTIVES: Exploring associations between the gut microbiota and colonic inflammation and assessing sequential changes during exclusive enteral nutrition (EEN) may offer clues into the microbial origins of Crohn's disease (CD). METHODS: Fecal samples (n=117) were collected from 23 CD and 21 healthy...

Subject

Metagenomics

Feces

Microbiome

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