Effect of Opioids vs NSAIDs and Larger vs Smaller Chest Tube Size on Pain Control and Pleurodesis Efficacy Among Patients With Malignant Pleural Effusion

M. Rahman, Najib; Pepperell, Justin; Rehal, Sunita; Saba, Tarek; Tang, Augustine; Ali, Nabeel; West, Alex; Hettiarachchi, Gihan; Mukherjee, Dipak; Samuel, Johnson; Bentley, Andrew; Dowson, Lee; Miles, Jonathan; Frank Ryan, C.; Y. Yoneda, Ken; Chauhan, Anoop; Corcoran, John; Psallidas, Ioannis; Wrightson, John; Hallifax, Rob; Davies, Helen; Lee, Gary; Dobson, Melissa; Hedley, Emma; Seaton, Douglas; Russell, Nicky; Chapman, Margaret; M. McFadyen, Bethan; Shaw, Rachel; J.O. Davies, Robert; Maskell, Nick; Nunn, Andrew; F. Miller, Robert

doi:10.1001/jama.2015.16840

Public

Effect of Opioids vs NSAIDs and Larger vs Smaller Chest Tube Size on Pain Control and Pleurodesis Efficacy Among Patients With Malignant Pleural Effusion

Published in JAMA • Dec 22, 2015

Authors:

Najib M. Rahman

Justin Pepperell

Sunita Rehal

Abstract

IMPORTANCE: For treatment of malignant pleural effusion, nonsteroidal anti-inflammatory drugs (NSAIDs) are avoided because they may reduce pleurodesis efficacy. Smaller chest tubes may be less painful than larger tubes, but efficacy in pleurodesis has not been proven. OBJECTIVE: To assess the effect...

Subject

Medicine

Chest tube

Pleurodesis

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