Familial Risk and Heritability of Cancer Among Twins in Nordic Countries

A. Mucci, Lorelei; Hjelmborg, Jacob; R. Harris, Jennifer; Czene, Kamila; J. Havelick, David; Scheike, Thomas; E. Graff, Rebecca; K. Holst, Klaus; Möller, Sören; Unger, Robert; McIntosh, Christina; Nuttall, Elizabeth; Brandt, Ingunn; L. Penney, Kathryn; Hartman, Mikael; Kraft, Peter; Parmigiani, Giovanni; Christensen, Kaare; Koskenvuo, Markku; V. Holm, Niels; Heikkilä, Kauko; Pukkala, ­Eero; Skytthe, Axel; Adami, Hans‐Olov; Kaprio, Jaakko

doi:10.1001/jama.2015.17703

Public

Familial Risk and Heritability of Cancer Among Twins in Nordic Countries

Published in JAMA • Jan 5, 2016

Authors:

Lorelei A. Mucci

Jacob Hjelmborg

Jennifer R. Harris

Abstract

IMPORTANCE: Estimates of familial cancer risk from population-based studies are essential components of cancer risk prediction. OBJECTIVE: To estimate familial risk and heritability of cancer types in a large twin cohort. DESIGN, SETTING, AND PARTICIPANTS: Prospective study of 80,309 monozygotic and...

Subject

Medicine

Heritability

Environmental health

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