Prevalence, clinical characteristics, and prognosis of GATA2-related myelodysplastic syndromes in children and adolescents

W. Włodarski, Marcin; Hirabayashi, Shinsuke; Manuel López Pastor, Víctor; Starý, Jan; Hasle, Henrik; Masetti, Riccardo; Dworzak, Michael; Schmugge, Markus; van den Heuvel‐Eibrink, Marry; Ussowicz, Marek; De Moerloose, Barbara; Català, Albert; Smith, Owen; Sedláček, Petr; C. Lankester, Arjan; Zecca, Marco; Bordon, Victoria; Matthes‐Martin, Susanne; Abrahamsson, Jonas; Kühl, J.; Sykora, Karl-Walter; H. Albert, Michael; Przychodzien, Bartlomiej; P. Maciejewski, Jaroslaw; Schwarz, Stephan; Göhring, Gudrun; Schlegelberger, Brigitte; Cseh, Annamária; Noellke, Peter; Yoshimi, Ayami; Locatelli, Franco; Baumann, Irith; Strahm, Brigitte; M. Niemeyer, Charlotte

doi:10.1182/blood-2015-09-669937

Public

Prevalence, clinical characteristics, and prognosis of GATA2-related myelodysplastic syndromes in children and adolescents

Published in Blood • Dec 24, 2015

Authors:

Marcin W. Włodarski

Shinsuke Hirabayashi

Víctor Manuel López Pastor

Abstract

Germline GATA2 mutations cause cellular deficiencies with high propensity for myeloid disease. We investigated 426 children and adolescents with primary myelodysplastic syndrome (MDS) and 82 cases with secondary MDS enrolled in 2 consecutive prospective studies of the European Working Group of MDS i...

Subject

Myelodysplastic syndromes

Medicine

Hematologic Neoplasms

Research Assistant

AI chat, annotations, notes & similar papers

Finding related papers...

Discussions

(0)

No comments yet

Be the first to share your thoughts!