Tumor-associated macrophages correlate with the clinicopathological features and poor outcomes via inducing epithelial to mesenchymal transition in oral squamous cell carcinoma

Hu, Yong; He, Mengying; Zhu, Lifang; Yang, Congchong; Zhou, Meiling; Wang, Qiong; Zhang, Wei; Zheng, Yangyu; Wang, Dongmiao; Xu, Zeng-Qi; Wu, Yunong; Liu, Laikui

doi:10.1186/s13046-015-0281-z

Public

Tumor-associated macrophages correlate with the clinicopathological features and poor outcomes via inducing epithelial to mesenchymal transition in oral squamous cell carcinoma

Published in Journal of Experimental & Clinical Cancer Research • Jan 15, 2016

Authors:

Yong Hu

Mengying He

Lifang Zhu

Abstract

BACKGROUND: Both tumor-associated macrophages (TAMs) and the epithelial to mesenchymal transition (EMT) of cancer cells play key roles in promoting tumor progression. However, whether TAMs could induce EMT in the progression of oral squamous cell carcinoma (OSCC) remains undefined. RESULTS: Here we ...

Subject

Epithelial–mesenchymal transition

Basal cell

Mesenchymal stem cell

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