PET Imaging of Macrophage Mannose Receptor–Expressing Macrophages in Tumor Stroma Using <sup>18</sup>F-Radiolabeled Camelid Single-Domain Antibody Fragments

Blykers, Anneleen; Schoonooghe, Steve; Xavier, Catarina; D’hoe, Kevin; Laoui, Damya; D’Huyvetter, Matthias; Vaneycken, Ilse; Cleeren, Frederik; Bormans, Guy; Heemskerk, Johannes; Raes, Geert; De Baetselier, Patrick; Lahoutte, Tony; Devoogdt, Nick; A. Van Ginderachter, Jo; Caveliers, Vicky

doi:10.2967/jnumed.115.156828

Public

PET Imaging of Macrophage Mannose Receptor–Expressing Macrophages in Tumor Stroma Using 18F-Radiolabeled Camelid Single-Domain Antibody Fragments

Published in Journal of Nuclear Medicine • Jun 11, 2015

Authors:

Anneleen Blykers

Steve Schoonooghe

Catarina Xavier

Abstract

UNLABELLED: Tumor-associated macrophages constitute a major component of the stroma of solid tumors, encompassing distinct subpopulations with different characteristics and functions. We aimed to identify M2-oriented tumor-supporting macrophages within the tumor microenvironment as indicators of can...

Subject

Biodistribution

In vivo

Mannose receptor

Research Assistant

AI chat, annotations, notes & similar papers

Finding related papers...

Discussions

(0)

No comments yet

Be the first to share your thoughts!