A Monocyte Conditioned Medium Is More Effective Than Defined Cytokines in Mediating the Terminal Maturation of Human Dendritic Cells

Reddy, Anita; Sapp, Mark; Feldman, Mary; Subklewe, Marion; Bhardwaj, Nina

doi:10.1182/blood.v90.9.3640

Public

A Monocyte Conditioned Medium Is More Effective Than Defined Cytokines in Mediating the Terminal Maturation of Human Dendritic Cells

Published in Blood • Nov 1, 1997

Authors:

Anita Reddy

Mark Sapp

Mary Feldman

Abstract

Mature human dendritic cells can be generated in substantial numbers from nonproliferating progenitors in human blood using a two-step protocol. T cell-depleted mononuclear cells are first cultured with granulocyte-macrophage colony-stimulating factor and interleukin-4 (IL-4) and then exposed to mon...

Subject

Dendritic cell

Cell biology

Biology

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