Polymorphisms in MIR137HG and microRNA-137-regulated genes influence gray matter structure in schizophrenia.

Wright, C; N Gupta, C; Chen, J; Patel, V; D Calhoun, V; Ehrlich, S; Wang, L; R Bustillo, J; I Perrone-Bizzozero, N; A Turner, J

doi:10.1038/tp.2015.211

Public

Polymorphisms in MIR137HG and microRNA-137-regulated genes influence gray matter structure in schizophrenia.

Shared by NobleBlocks on Feb 2, 2016 • 12:00 AM UTC

Authors:

C Wright

C N Gupta

J Chen

Abstract

Evidence suggests that microRNA-137 (miR-137) is involved in the genetic basis of schizophrenia. Risk variants within the miR-137 host gene (MIR137HG) influence structural and functional brain-imaging measures, and miR-137 itself is predicted to regulate hundreds of genes. We evaluated the influence...

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