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Studies on the Carcinogenic Activity of Protein-Denaturing Agents: Hepatocarcinogenicity of Dioxane<xref ref-type="fn" rid="FN2">2</xref>

Published in JNCI Journal of the National Cancer Institute • Dec 1, 1965
Authors:
Mary F. Argus
,
Joseph C. Arcos
,
Cornelia Hoch‐Ligeti

Abstract

The carcinogenic activity of diethylformamide, diethylacetamide, N,N′-dimethyl-N,N′-dinitrosophthalamide, heptylamine, and dioxane, compounds selected both because of their potency to denature proteins and their structural resemblance to nitrosamine derivatives, was investigated. Dioxane, when admin...

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