Perfluorocarbon nanoparticles enhance reactive oxygen levels and tumour growth inhibition in photodynamic therapy

Cheng, Yuhao; Cheng, Hao; Jiang, Chenxiao; Qiu, Xuefeng; Wang, Kaikai; Wei, Huan; Yuan, Ahu; Wu, Jinhui; Hu, Yiqiao

doi:10.1038/ncomms9785

Public

Perfluorocarbon nanoparticles enhance reactive oxygen levels and tumour growth inhibition in photodynamic therapy

Published in Nature Communications • Nov 3, 2015

Authors:

Yuhao Cheng

Hao Cheng

Chenxiao Jiang

Abstract

Photodynamic therapy (PDT) kills cancer cells by converting tumour oxygen into reactive singlet oxygen ((1)O2) using a photosensitizer. However, pre-existing hypoxia in tumours and oxygen consumption during PDT can result in an inadequate oxygen supply, which in turn hampers photodynamic efficacy. H...

Subject

Photodynamic therapy

Reactive oxygen species

Nanoparticle

Research Assistant

AI chat, annotations, notes & similar papers

Finding related papers...

Discussions

(0)

No comments yet

Be the first to share your thoughts!