Exome-wide association analysis reveals novel coding sequence variants associated with lipid traits in Chinese

Sze-Man Tang, Clara; Zhang, He; Y. Y. Cheung, Chloe; Xu, Ming; Ho, Jenny; Zhou, Wei; S. Cherny, Stacey; Zhang, Yan; L. Holmen, Oddgeir; Au, Ka‐Wing; Yu, Haiyi; Xu, Lin; Jia, Jia; M. Porsch, Robert; Sun, Lijie; Xu, Weixian; Zheng, Huiping; Wong, Lai-Yung; Mu, Yiming; Dou, Jing–tao; Ho-Yan Fong, Carol; Wang, Shuyu; Hong, Xueyu; Dong, Liguang; Liao, Yanhua; Wang, Jiansong; Suk Mi Lam, Levina; Su, Xi; Yan, Hua; Yang, Min‐Lee; Chen, Jin; Siu, Chung-Wah; Xie, Gaoqiang; Cho Woo, Yu; Wu, Yangfeng; Choon Beng Tan, Kathryn; Hveem, Kristian; M.Y. Cheung, Bernard; Zöllner, Sebastian; Xu, Aimin; Eugene Chen, Y; Qiang Jiang, Chao; Zhang, Youyi; Lam, Tai-Hing; K. Ganesh, Santhi; Huo, Yong; C. Sham, Pak; S.L. Lam, Karen; J. Willer, Cristen; Tse, Hung‐Fat; Gao, Wei

doi:10.1038/ncomms10206

Public

Exome-wide association analysis reveals novel coding sequence variants associated with lipid traits in Chinese

Published in Nature Communications • Dec 22, 2015

Authors:

Clara Sze-Man Tang

He Zhang

Chloe Y. Y. Cheung

Abstract

Blood lipids are important risk factors for coronary artery disease (CAD). Here we perform an exome-wide association study by genotyping 12,685 Chinese, using a custom Illumina HumanExome BeadChip, to identify additional loci influencing lipid levels. Single-variant association analysis on 65,671 si...

Subject

Exome sequencing

Genetics

Exome

Research Assistant

AI chat, annotations, notes & similar papers

Finding related papers...

Discussions

(0)

No comments yet

Be the first to share your thoughts!