Identification of new susceptibility loci for IgA nephropathy in Han Chinese

Li, Ming; Nee Foo, Jia; Wang, Jin-Quan; Low, Hui-Qi; Tang, Xue-Qing; Yee Toh, Kai; Yin, Pei-Ran; Chuen Khor, Chiea; Goh, Yu-Fen; D. Irwan, Ishak; Xu, Ri-Cong; Kumar Andiappan, Anand; Bei, Jin‐Xin; Rötzschke, Olaf; Chen, Menghua; Cheng, Ching‐Yu; Sun, Liang-Dan; Jiang, Geng-Ru; Yin Wong, Tien; Lin, Hong-Li; Aung, Tin; Liao, Yun-Hua; Saw, Seang‐Mei; Ye, Kun; P. Ebstein, Richard; Chen, Qin-Kai; Shi, Wei; Hong Chew, Soo; Chen, Jian; Zhang, Fu-Ren; Li, Shengping; Xu, Gang; Shyong Tai, E; Wang, Li; Chen, Nan; Zhang, Xuejun; Zeng, Yi-Xin; Zhang, Hong; Liu, Zhi-Hong; Yu, Xue-Qing; Liu, Jianjun

doi:10.1038/ncomms8270

Public

Identification of new susceptibility loci for IgA nephropathy in Han Chinese

Published in Nature Communications • Jun 1, 2015

Authors:

Ming Li

Jia Nee Foo

Jin-Quan Wang

Abstract

IgA nephropathy (IgAN) is one of the most common primary glomerulonephritis. Previously identified genome-wide association study (GWAS) loci explain only a fraction of disease risk. To identify novel susceptibility loci in Han Chinese, we conduct a four-stage GWAS comprising 8,313 cases and 19,680 c...

Subject

Genome-wide association study

Odds ratio

Biology

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