A 2-Year Randomized Controlled Trial of Human Caloric Restriction: Feasibility and Effects on Predictors of Health Span and Longevity.

Eric, Ravussin,; Leanne M, Redman,; James, Rochon,; Sai Krupa, Das,; Luigi, Fontana,; William E, Kraus,; Sergei, Romashkan,; Donald A, Williamson,; Simin N, Meydani,; Dennis T, Villareal,; Steven R, Smith,; Richard I, Stein,; Tammy M, Scott,; Tiffany M, Stewart,; Edward, Saltzman,; Samuel, Klein,; Manju, Bhapkar,; Corby K, Martin,; Cheryl H, Gilhooly,; John O, Holloszy,; Evan C, Hadley,; Susan B, Roberts,

doi:10.1093/gerona/glv057

Public

A 2-Year Randomized Controlled Trial of Human Caloric Restriction: Feasibility and Effects on Predictors of Health Span and Longevity.

Published in The journals of gerontology. Series A, Biological sciences and medical sciences • Sep 1, 2015

Authors:

Ravussin, Eric

Redman, Leanne M

Rochon, James

Abstract

BACKGROUND: Caloric restriction (CR), energy intake reduced below ad libitum (AL) intake, increases life span in many species. The implications for humans can be clarified by randomized controlled trials of CR. METHODS: To determine CR's feasibility, safety, and effects on predictors of longevity, d...

Subject

Biomarkers

Caloric restriction

Metabolism

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