Lack of Effect of Adjuvant Chemotherapy on the Elimination of Single Dormant Tumor Cells in Bone Marrow of High-Risk Breast Cancer Patients

Braun, Stephan; Kentenich, Christina; Janni, Wolfgang; Hepp, F.; De Waal, J.; Willgeroth, F; Sommer, Harald; Pantel, Klaus

doi:10.1200/jco.2000.18.1.80

Public

Lack of Effect of Adjuvant Chemotherapy on the Elimination of Single Dormant Tumor Cells in Bone Marrow of High-Risk Breast Cancer Patients

Published in Journal of Clinical Oncology • Jan 1, 2000

Authors:

Stephan Braun

Christina Kentenich

Wolfgang Janni

Abstract

PURPOSE: There is an urgent need for markers that can predict the efficacy of adjuvant chemotherapy in patients with solid tumors. This study was designed to evaluate whether monitoring of micrometastases in bone marrow can predict the response to systemic chemotherapy in breast cancer. PATIENTS AND...

Subject

Medicine

Breast cancer

Bone marrow

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