Recombinant gibbon interleukin 3 supports formation of human multilineage colonies and blast cell colonies in culture: comparison with recombinant human granulocyte-macrophage colony-stimulating factor

Leary, AG; Yang, YC; Clark, SC; Gasson, JC; Golde, DW; Ogawa, Makio

doi:10.1182/blood.v70.5.1343.1343

Public

Recombinant gibbon interleukin 3 supports formation of human multilineage colonies and blast cell colonies in culture: comparison with recombinant human granulocyte-macrophage colony-stimulating factor

Published in Blood • Nov 1, 1987

Authors:

AG Leary

YC Yang

SC Clark

Abstract

The genetic sequences encoding the gibbon and human interleukin 3 (IL 3) proteins were molecularly cloned. The amino acid sequence of the mature gibbon IL 3 protein proved to share 93% homology with the corresponding human protein. We examined the effects of biosynthetic (recombinant) gibbon IL 3 on...

Subject

Biology

Recombinant DNA

Progenitor cell

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