Adjunctive Dexamethasone in HIV-Associated Cryptococcal Meningitis

Beardsley, Justin; Wolbers, Marcel; Kibengo, Freddie; Ggayi, Abu-Baker; Kamali, Anatoli; Thi Kim Cuc, Ngo; Quang Bình, Trần; Văn Vĩnh Châu, Nguyễn; Farrar, Jeremy; Merson, Laura; Phuong, Lan; Thwaites, Guy; Văn Kính, Nguyễn; Thanh Thuy, Pham; Chierakul, Wirongrong; Siriboon, Suwatthiya; Thiansukhon, Ekkachai; Onsanit, Satrirat; Supphamongkholchaikul, Watthanapong; K Chan, Adrienne; S. Heyderman, Robert; Mwinjiwa, Edson; J. van Oosterhout, Joep; Imran, Darma; Basri, Hasan; Mayxay, Mayfong; A. B. Dance, David; Phimmasone, Prasith; Rattanavong, Sayaphet; G. Lalloo, David; Day, Jeremy

doi:10.1056/nejmoa1509024

Public

Adjunctive Dexamethasone in HIV-Associated Cryptococcal Meningitis

Published in New England Journal of Medicine • Feb 11, 2016

Authors:

Justin Beardsley

Marcel Wolbers

Freddie Kibengo

Abstract

BACKGROUND: Cryptococcal meningitis associated with human immunodeficiency virus (HIV) infection causes more than 600,000 deaths each year worldwide. Treatment has changed little in 20 years, and there are no imminent new anticryptococcal agents. The use of adjuvant glucocorticoids reduces mortality...

Subject

Medicine

Cryptococcal meningitis

Dexamethasone

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