Mitochondria and Mitochondrial ROS in Cancer: Novel Targets for Anticancer Therapy

Yang, Yuhui; Karakhanova, Svetlana; Hartwig, Werner; D’Haese, Jan; P. Philippov, Pavel; Werner, Jens; V. Bazhin, Alexandr

doi:10.1002/jcp.25349

Public

Mitochondria and Mitochondrial ROS in Cancer: Novel Targets for Anticancer Therapy

Published in Journal of Cellular Physiology • Feb 20, 2016

Authors:

Yuhui Yang

Svetlana Karakhanova

Werner Hartwig

Abstract

Mitochondria are indispensable for energy metabolism, apoptosis regulation, and cell signaling. Mitochondria in malignant cells differ structurally and functionally from those in normal cells and participate actively in metabolic reprogramming. Mitochondria in cancer cells are characterized by react...

Subject

Mitochondrion

Oxidative phosphorylation

Cancer cell

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