A study of the mechanisms underlying the anti-inflammatory effect of ellagic acid in carrageenan-induced paw edema in rats

Ghorbanzadeh, Behnam; Taghi Mansouri, Mohammad; Asghar Hemmati, Ali; Naghizadeh, Bahareh; Ali Mard, Seyyed; Rezaie, Annahita

doi:10.4103/0253-7613.157127

Public

A study of the mechanisms underlying the anti-inflammatory effect of ellagic acid in carrageenan-induced paw edema in rats

Published in Indian Journal of Pharmacology • Jan 1, 2015

Authors:

Behnam Ghorbanzadeh

Mohammad Taghi Mansouri

Ali Asghar Hemmati

Abstract

OBJECTIVES: Ellagic acid (EA) has shown antinociceptive and anti-inflammatory effects. Inducible nitric oxide synthase (iNOS), cyclooxygenase 2 (COX-2) enzymes and also cytokines play a key role in many inflammatory conditions. This study was aimed to investigate the mechanisms involved in the anti-...

Subject

Carrageenan

Nitric oxide synthase

Inflammation

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