Plasma Branched-Chain Amino Acids and Incident Cardiovascular Disease in the PREDIMED Trial

Ruiz-Canela, Miguel; Toledo, Estefania; B Clish, Clary; Hruby, Adela; Liang, Liming; Salas-Salvadó, Jordi; Razquin, Cristina; Corella, Dolores; Estruch, Ramón; Ros, Emilio; Fitó, Montserrat; Gómez-Gracia, Enrique; Arós, Fernando; Fiol, Miquel; Lapetra, José; Serra-Majem, Lluis; A Martínez-González, Miguel; B Hu, Frank

doi:10.1373/clinchem.2015.251710

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Plasma Branched-Chain Amino Acids and Incident Cardiovascular Disease in the PREDIMED Trial

Shared by NobleBlocks on Apr 1, 2016 • 12:00 AM UTC

Authors:

Miguel Ruiz-Canela

Estefania Toledo

Clary B Clish

Abstract

Abstract BACKGROUND The role of branched-chain amino acids (BCAAs) in cardiovascular disease (CVD) remains poorly understood. We hypothesized that baseline BCAA concentrations predict future risk of CVD and that a Mediterranean diet (MedDiet) intervention may counteract this effect. METHODS We devel...

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