Effect of Insulin Glargine Up-titration vs Insulin Degludec/Liraglutide on Glycated Hemoglobin Levels in Patients With Uncontrolled Type 2 Diabetes

Lingvay, Ildiko; Pérez Manghi, Federico; Alberto García-Hernández, Pedro; Norwood, Paul; Lehmann, Lucine; Jeppe Tarp-Johansen, Mads; B. Buse, John; the DUAL V Investigators, for

doi:10.1001/jama.2016.1252

Public

Effect of Insulin Glargine Up-titration vs Insulin Degludec/Liraglutide on Glycated Hemoglobin Levels in Patients With Uncontrolled Type 2 Diabetes

Published in JAMA • Mar 1, 2016

Authors:

Ildiko Lingvay

Federico Pérez Manghi

Pedro Alberto García-Hernández

Abstract

IMPORTANCE: Achieving glycemic control remains a challenge for patients with type 2 diabetes, even with insulin therapy. OBJECTIVE: To assess whether a fixed ratio of insulin degludec/liraglutide was noninferior to continued titration of insulin glargine in patients with uncontrolled type 2 diabetes...

Subject

Medicine

Insulin glargine

Liraglutide

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