The Number of Parvalbumin-Expressing Interneurons Is Decreased in the Medial Prefrontal Cortex in Autism

Hashemi, Ezzat; Ariza, Jeanelle; Rogers, Haille; C. Noctor, Stephen; Martínez‐Cerdeño, Verónica

doi:10.1093/cercor/bhw021

Public

The Number of Parvalbumin-Expressing Interneurons Is Decreased in the Medial Prefrontal Cortex in Autism

Published in Cerebral Cortex • Feb 27, 2016

Authors:

Ezzat Hashemi

Jeanelle Ariza

Haille Rogers

Abstract

The cognitive phenotype of autism has been correlated with an altered balance of excitation to inhibition in the cerebral cortex, which could result from a change in the number, function, or morphology of GABA-expressing interneurons. The number of GABAergic interneuron subtypes has not been quantif...

Subject

Parvalbumin

Interneuron

Calretinin

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