Blood lipids and prostate cancer: a Mendelian randomization analysis

J. Bull, Caroline; Bonilla, Carolina; M.P. Holly, Jeff; M. Perks, Claire; M Davies, Neil; Haycock, Philip; Hoi Yun Yu, Oriana; Brent Richards, J.; A. Eeles, Rosalind; Easton, Doug; Kote‐Jarai, Zsofia; Amin Al Olama, Ali; Benlloch, Sara; Muir, Kenneth; G. Giles, Graham; J. MacInnis, Robert; Wiklund, Fredrik; Grönberg, Henrik; A. Haiman, Christopher; Schleutker, Johanna; G. Nordestgaard, Børge; C. Travis, Ruth; E. Neal, David; Pashayan, Nora; Khaw, Kay‐Tee; L. Stanford, Janet; J. Blot, William; N. Thibodeau, Stephen; Maier, Christiane; S. Kibel, Adam; Cybulski, Cezary; Cannon‐Albright, Lisa; Brenner, Hermann; Park, Jong; Kaneva, Radka; Batra, Jyotsna; R. Teixeira, Manuel; Micheal, Agnieszka; Pandha, Hardev; Davey Smith, George; J. Lewis, Sarah; M. Martin, Richard

doi:10.1002/cam4.695

Public

Blood lipids and prostate cancer: a Mendelian randomization analysis

Published in Cancer Medicine • Mar 19, 2016

Authors:

Caroline J. Bull

Carolina Bonilla

Jeff M.P. Holly

Abstract

Genetic risk scores were used as unconfounded instruments for specific lipid traits (Mendelian randomization) to assess whether circulating lipids causally influence prostate cancer risk. Data from 22,249 prostate cancer cases and 22,133 controls from 22 studies within the international PRACTICAL co...

Subject

Mendelian randomization

Prostate cancer

Odds ratio

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