A novel gene, optrA, that confers transferable resistance to oxazolidinones and phenicols and its presence in Enterococcus faecalis and Enterococcus faecium of human and animal origin

Wang, Yang; Lv, Yuan; Cai, Jiachang; Schwarz, Štefan; Cui, Lanqing; Hu, Zhidong; Zhang, Rong; Li, Jun; Zhao, Qin; He, Tao; Wang, Dacheng; Wang, Zheng; Shen, Yingbo; Li, Yun; T. Feßler, Andrea; Wu, Congming; Yu, Hao; Deng, Xuming; Xia, Xi; Shen, Jianzhong

doi:10.1093/jac/dkv116

Public

A novel gene, optrA, that confers transferable resistance to oxazolidinones and phenicols and its presence in Enterococcus faecalis and Enterococcus faecium of human and animal origin

Published in Journal of Antimicrobial Chemotherapy • May 14, 2015

Authors:

Yang Wang

Yuan Lv

Jiachang Cai

Abstract

OBJECTIVES: The oxazolidinone-resistant Enterococcus faecalis E349 from a human patient tested negative for the cfr gene and 23S rRNA mutations. Here we report the identification of a novel oxazolidinone resistance gene, optrA, and a first investigation of the extent to which this gene was present i...

Subject

Enterococcus faecalis

Enterococcus faecium

Enterococcus

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