VISFATIN (NAMPT) Improves in Vitro IGF1-Induced Steroidogenesis and IGF1 Receptor Signaling Through SIRT1 in Bovine Granulosa Cells1

Reverchon, Maxime; Ramé, Christelle; Bunel, Audrey; Chen, Wenyong; Froment, Pascal; Dupont, Joëlle

doi:10.1095/biolreprod.115.134650

Public

VISFATIN (NAMPT) Improves in Vitro IGF1-Induced Steroidogenesis and IGF1 Receptor Signaling Through SIRT1 in Bovine Granulosa Cells1

Published in Biology of Reproduction • Jan 21, 2016

Authors:

Maxime Reverchon

Christelle Ramé

Audrey Bunel

Abstract

VISFATIN is a novel adipokine, also known as a nicotinamide phosphorybosyltransferase (NAMPT), that is able to modulate different processes, including lipid and glucose metabolism, oxidative stress, inflammation, and insulin resistance. Recent data suggest that it also plays a role in reproductive f...

Subject

Endocrinology

Internal medicine

Theca

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