Chaperonin Containing TCP-1 Protein Level in Breast Cancer Cells Predicts Therapeutic Application of a Cytotoxic Peptide

Bassiouni, Rania; N. Nemec, Kathleen; Iketani, Ashley; Flores, Orielyz; Showalter, Anne; S. Khaled, Amr; Vishnubhotla, Priya; W. Sprung, Robert; Kaittanis, Charalambos; Manuel Perez, J.; R. Khaled, Annette

doi:10.1158/1078-0432.ccr-15-2502

Public

Chaperonin Containing TCP-1 Protein Level in Breast Cancer Cells Predicts Therapeutic Application of a Cytotoxic Peptide

Published in Clinical Cancer Research • Mar 24, 2016

Authors:

Rania Bassiouni

Kathleen N. Nemec

Ashley Iketani

Abstract

PURPOSE: Metastatic disease is a leading cause of death for patients with breast cancer, driving the need for new therapies. CT20p is a peptide previously discovered by our group that displays cancer-specific cytotoxicity. To design the optimal therapeutic use of the peptide, we identified the intra...

Subject

Breast cancer

Cancer cell

Cancer

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