The Circular RNA Cdr1as Promotes Myocardial Infarction by Mediating the Regulation of miR-7a on Its Target Genes Expression

Geng, Hai-Hua; Li, Rui; Su, Yamin; Xiao, Jie; Pan, Min; Cai, Xingxing; Ji, Xiaoping

doi:10.1371/journal.pone.0151753

Public

The Circular RNA Cdr1as Promotes Myocardial Infarction by Mediating the Regulation of miR-7a on Its Target Genes Expression

Published in PLoS ONE • Mar 21, 2016

Authors:

Hai-Hua Geng

Rui Li

Yamin Su

Abstract

OBJECTIVES: Recent studies have demonstrated the role of Cdr1as (or CiRS-7), one of the well-identified circular RNAs (circRNAs), as a miR-7a/b sponge or inhibitor in brain tissues or islet cells. This study aimed to investigate the presence of Cdr1as/miR-7a pathway in cardiomyocytes, and explore th...

Subject

Apoptosis

Transfection

Flow cytometry

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