Oxidative stress in retinal pigment epithelium cells increases exosome secretion and promotes angiogenesis in endothelial cells

Atienzar‐Aroca, Sandra; Flores‐Bellver, Miguel; Serrano‐Heras, Gemma; Martínez‐Gil, Natalia; M. Barcia, Jorge; Ferrer Aparicio, S.; Pérez‐Cremades, Daniel; Manuel García‐Verdugo, José; Díaz-Llopis, M.; J. Romero, Francisco; Sancho-Pellúz, Javier

doi:10.1111/jcmm.12834

Public

Oxidative stress in retinal pigment epithelium cells increases exosome secretion and promotes angiogenesis in endothelial cells

Published in Journal of Cellular and Molecular Medicine • Mar 21, 2016

Authors:

Sandra Atienzar‐Aroca

Miguel Flores‐Bellver

Gemma Serrano‐Heras

Abstract

The retinal pigment epithelium (RPE), a monolayer located between the photoreceptors and the choroid, is constantly damaged by oxidative stress, particularly because of reactive oxygen species (ROS). As the RPE, because of its physiological functions, is essential for the survival of the retina, any...

Subject

Microvesicles

Cell biology

Retinal pigment epithelium

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