Radiation plus Procarbazine, CCNU, and Vincristine in Low-Grade Glioma

C. Buckner, Jan; G. Shaw, Edward; L. Pugh, Stephanie; Chakravarti, Arnab; R. Gilbert, Mark; Barger, Geoffrey; W. Coons, Stephen; E. Ricci, Peter; E. Bullard, Dennis; D. Brown, Paul; Stelzer, K.; Brachman, David; H. Suh, John; J. Schultz, Christopher; Bahary, Jean-Paul; J. Fisher, Barbara; Kim, Harold; Murtha, Albert; H. Bell, Erica; Won, Minhee; P. Mehta, Minesh; J. Curran, Walter

doi:10.1056/nejmoa1500925

Public

Radiation plus Procarbazine, CCNU, and Vincristine in Low-Grade Glioma

Published in New England Journal of Medicine • Apr 6, 2016

Authors:

Jan C. Buckner

Edward G. Shaw

Stephanie L. Pugh

Abstract

BACKGROUND: Grade 2 gliomas occur most commonly in young adults and cause progressive neurologic deterioration and premature death. Early results of this trial showed that treatment with procarbazine, lomustine (also called CCNU), and vincristine after radiation therapy at the time of initial diagno...

Subject

Medicine

Procarbazine

Lomustine

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