Prevention of a First Stroke by Transfusions in Children with Sickle Cell Anemia and Abnormal Results on Transcranial Doppler Ultrasonography

J. Adams, Robert; C. McKie, Virgil; L. Hsu, Lewis; Files, Beatrice; Vichinsky, Elliott; Pegelow, Charles; R. Abboud, Miguel; Gallagher, Dianne; Kutlar, Abdullah; T. Nichols, Fenwick; R. Bonds, Duane; Brambilla, Donald; Woods, Gerald; Olivieri, Nancy; Driscoll, Catherine; Miller, Scott; Wang, Winfred; Hurlett, Anne; Scher, Charles; Berman, Brian; Carl, Elizabeth; M. Jones, Anne; Steve Roach, E.; Wright, Elizabeth; A. Zimmerman, Robert; Waclawiw, Myron

doi:10.1056/nejm199807023390102

Public

Prevention of a First Stroke by Transfusions in Children with Sickle Cell Anemia and Abnormal Results on Transcranial Doppler Ultrasonography

Published in New England Journal of Medicine • Jul 2, 1998

Authors:

Robert J. Adams

Virgil C. McKie

Lewis L. Hsu

Abstract

BACKGROUND: Blood transfusions prevent recurrent stroke in children with sickle cell anemia, but the value of transfusions in preventing a first stroke is unknown. We used transcranial Doppler ultrasonography to identify children with sickle cell anemia who were at high risk for stroke and then rand...

Subject

Medicine

Stroke (engine)

Transcranial Doppler

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