Alendronate for the Prevention and Treatment of Glucocorticoid-Induced Osteoporosis

G. Saag, Kenneth; Emkey, Ronald; J. Schnitzer, Thomas; P. Brown, Jacques; Hawkins, Federico; Goemaere, Stefan; Thamsborg, Gorm; Liberman, Uri; D. Delmas, Pierre; Malice, Marie‐Pierre; Czachur, Michelle; G. Daifotis, Anastasia; E. Lane, Nancy; Correa-Rotter, Ricardo; Yanover, Melissa; Westhovens, René; Epstein, Sol; D. Adachi, Jonathan; E. Poubelle, Patrice; Melo‐Gomes, José; Adolfo Rodriguez-Portales, Jose

doi:10.1056/nejm199807303390502

Public

Alendronate for the Prevention and Treatment of Glucocorticoid-Induced Osteoporosis

Published in New England Journal of Medicine • Jul 30, 1998

Authors:

Kenneth G. Saag

Ronald Emkey

Thomas J. Schnitzer

Abstract

BACKGROUND: Osteoporosis is a common complication of long-term glucocorticoid therapy for which there is no well-proved preventive or restorative treatment. METHODS: We carried out two 48-week, randomized, placebo-controlled studies of two doses of alendronate in 477 men and women, 17 to 83 years of...

Subject

Medicine

Osteoporosis

Placebo

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