Selective Stimulation of Cardiac Lymphangiogenesis Reduces Myocardial Edema and Fibrosis Leading to Improved Cardiac Function Following Myocardial Infarction

Henri, Orianne; Pouehe, Chris; Houssari, Mahmoud; Galas, Ludovic; Nicol, Lionel; Edwards-Lévy, Florence; Henry, Jean-Paul; Dumesnil, Anais; Boukhalfa, Inès; Banquet, Sébastien; Schapman, Damien; Thuillez, Christian; Richard, Vincent; Mulder, Paul; Brakenhielm, Ebba

doi:10.1161/circulationaha.115.020143

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Selective Stimulation of Cardiac Lymphangiogenesis Reduces Myocardial Edema and Fibrosis Leading to Improved Cardiac Function Following Myocardial Infarction

Shared by NobleBlocks on Apr 12, 2016 • 12:00 AM UTC

Authors:

Orianne Henri

Chris Pouehe

Mahmoud Houssari

Abstract

Background— The lymphatic system regulates interstitial tissue fluid balance, and lymphatic malfunction causes edema. The heart has an extensive lymphatic network displaying a dynamic range of lymph flow in physiology. Myocardial edema occurs in many cardiovascular diseases, eg, myocardial infarctio...

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