Metabolic Effects of Metformin in Non-Insulin-Dependent Diabetes Mellitus

Stümvoll, Michael; Nurjhan, N.; Perriello, G.; Dailey, George; E. Gerich, John

doi:10.1056/nejm199508313330903

Public

Metabolic Effects of Metformin in Non-Insulin-Dependent Diabetes Mellitus

Published in New England Journal of Medicine • Aug 31, 1995

Authors:

Michael Stümvoll

N. Nurjhan

G. Perriello

Abstract

BACKGROUND: The metabolic effects and mechanism of action of metformin are still poorly understood, despite the fact that it has been used to treat patients with non-insulin-dependent diabetes mellitus (NIDDM) for more than 30 years. METHODS: In 10 obese patients with NIDDM, we used a combination of...

Subject

Metformin

Medicine

Diabetes mellitus

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