Antibacterial Activity of Sulfamethoxazole Transformation Products (TPs): General Relevance for Sulfonamide TPs Modified at the <i>para</i> Position

Majewsky, Marius; Wagner, Danny; Delay, Markus; Bräse, Stefan; Yargeau, Viviane; Horn, Harald

doi:10.1021/tx500267x

Public

Antibacterial Activity of Sulfamethoxazole Transformation Products (TPs): General Relevance for Sulfonamide TPs Modified at the para Position

Published in Chemical Research in Toxicology • Aug 29, 2014

Authors:

Marius Majewsky

Danny Wagner

Markus Delay

Abstract

Sulfonamide antibiotics undergo transformation in the aquatic environment through biodegradation, photolysis, or hydrolysis. In this study, the residual antibacterial activity of 11 transformation products (TPs) of sulfamethoxazole (SMX) was investigated with regard to their in vitro growth and lumi...

Subject

Sulfonamide

Sulfamethoxazole

Chemistry

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