Reduction of Maternal-Infant Transmission of Human Immunodeficiency Virus Type 1 with Zidovudine Treatment

M. Connor, Edward; Sperling, Rhoda; D. Gelber, Richard; Kiselev, P.N.; B. Scott, Gwendolyn; Jo O’Sullivan, Mary; VanDyke, Russell; Bey, Mohammed; T. Shearer, William; L. Jacobson, Robert; Jiménez, Eleanor; H. O'Neill, Edward; Bazin, Brigitte; Delfraissy, Jean-François; Culnane, Mary; W. Coombs, Robert; Elkins, Mary; Moye, Jack; Stratton, Pamela; Balsley, James

doi:10.1056/nejm199411033311801

Public

Reduction of Maternal-Infant Transmission of Human Immunodeficiency Virus Type 1 with Zidovudine Treatment

Published in New England Journal of Medicine • Nov 3, 1994

Authors:

Edward M. Connor

Rhoda Sperling

Richard D. Gelber

Abstract

BACKGROUND AND METHODS: Maternal-infant transmission is the primary means by which young children become infected with human immunodeficiency virus type 1 (HIV). We conducted a randomized, double-blind, placebo-controlled trial of the efficacy and safety of zidovudine in reducing the risk of materna...

Subject

Zidovudine

Medicine

Regimen

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