Comparison of Amphotericin B with Fluconazole in the Treatment of Acute AIDS-Associated Cryptococcal Meningitis

S. Saag, Michael; G. Powderly, William; A. Cloud, Gretchen; Robinson, Patrick; H. Grieco, Michael; K. Sharkey, P.; E. Thompson, Sumner; M. Sugar, Alan; U. Tuazon, Carmelita; F. Fisher, John; Hyslop, N.; M. Jacobson, Jeffrey; Hafner, Richard; E. Dismukes, William

doi:10.1056/nejm199201093260202

Public

Comparison of Amphotericin B with Fluconazole in the Treatment of Acute AIDS-Associated Cryptococcal Meningitis

Published in New England Journal of Medicine • Jan 9, 1992

Authors:

Michael S. Saag

William G. Powderly

Gretchen A. Cloud

Abstract

BACKGROUND: Intravenous amphotericin B, with or without flucytosine, is usually standard therapy for cryptococcal meningitis in patients with the acquired immunodeficiency syndrome (AIDS). Fluconazole, an oral triazole agent, represents a promising new approach to the treatment of cryptococcal disea...

Subject

Fluconazole

Flucytosine

Medicine

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