Tertiary DNA Structure in the Single-Stranded hTERT Promoter Fragment Unfolds and Refolds by Parallel Pathways via Cooperative or Sequential Events

Yu, Zhongbo; C. Gaerig, Vanessa; Cui, Yunxi; Kang, Hyun-Jin; Gokhale, Vijay; Zhao, Yuan; H. Hurley, Laurence; Mao, Hanbin

doi:10.1021/ja210399h

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Tertiary DNA Structure in the Single-Stranded hTERT Promoter Fragment Unfolds and Refolds by Parallel Pathways via Cooperative or Sequential Events

Published in Journal of the American Chemical Society • Feb 28, 2012

Authors:

Zhongbo Yu

Vanessa C. Gaerig

Yunxi Cui

Abstract

The discovery of G-quadruplexes and other DNA secondary elements has increased the structural diversity of DNA well beyond the ubiquitous double helix. However, it remains to be determined whether tertiary interactions can take place in a DNA complex that contains more than one secondary structure. ...

Subject

Chemistry

DNA

Biophysics

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